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L-Selectin antibody

The Mouse Monoclonal anti-L-Selectin antibody has been validated for ELISA and Coat. It is suitable to detect L-Selectin in samples from Human.
Catalog No. ABIN6938361

Quick Overview for L-Selectin antibody (ABIN6938361)

Target

See all L-Selectin (SELL) Antibodies
L-Selectin (SELL) (Selectin L (SELL))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This L-Selectin antibody is un-conjugated

Application

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ELISA, Coating (Coat)

Clone

CD62L-1588
  • Specificity

    Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

    Cross-Reactivity (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    MAb raised against supernatant from phorbol myristic acid activated human peripheral blood leukocytes.

    Isotype

    IgG1 kappa
  • Application Notes

    Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    Positive_Control: HPBL or Jurkat whole cell lysate.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Preservative

    Azide free

    Storage

    -20 °C,-80 °C

    Storage Comment

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Expiry Date

    24 months
  • Target

    L-Selectin (SELL) (Selectin L (SELL))

    Alternative Name

    SELL

    Background

    A.11, AI528707, CD62 antigen ligand, CD62L, gp90-MEL, IgA nephropathy, susceptibility to, included, L Selectin, L-selectin, LAM1, LECAM1, LEU8, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lnhr, LSEL, Ly-22, LYAM1, Lymph node homing receptor, Lymphocyte antigen 22, Lymphocyte surface MEL-14 antigen, Pln homing receptor, PLNHR, SELL, TQ1,CD62L (L-Selectin)
    Cellular localisation: Cytoplasmic.

    Molecular Weight

    65-75kDa

    Gene ID

    6402, 728756

    UniProt

    P14151
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