SLC3A2 antibody

Catalog No. ABIN6938400

Product Details anti-SLC3A2 Antibody

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC3A2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Molt 13 T cell line

Clone: UM7F8

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs, Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HL-60, Jurkat, MG63, HUT-78, K562, YT, U937, Hep-G2 cells, Tonsil.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for SLC3A2

Target: SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Alternative Name: SLC3A2 (SLC3A2 Products)

Background: 4F2, 4F2HC, 4T2HC, CD98C, MDU1, NACAE, Slc3a2, Solute Carrier Family 3 (activators of dibasic and neutral amino acid transport) Member 2, E16, LAT1, MPE16, hLAT1,CD98 (SLC3A2)
Cellular localisation: Cell surface, cytoplasmic

Molecular Weight: Heterodimer (125kDa) made of a disulfide-linked glycosylated heavy chain of approximately 80-90kDa and a non-glycosylated light chain

Gene ID: 6520, 502769

UniProt: P08195