WIPI2 antibody (AA 418-436)

Catalog No. ABIN6938781

The Mouse Monoclonal anti-WIPI2 antibody has been validated for ELISA, Coat and FACS. It is suitable to detect WIPI2 in samples from Human.

Quick Overview for WIPI2 antibody (AA 418-436) (ABIN6938781)

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WIPI2 antibody is un-conjugated

Application: ELISA, Coating (Coat), Flow Cytometry (FACS)

Clone: 2A2

Product Details anti-WIPI2 Antibody

Binding Specificity: AA 418-436

Specificity: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).

Cross-Reactivity (Details): Human. Mouse.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa 418-436) of human WIPI2 protein (exact sequence is proprietary)

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells), Optimal dilution for a specific application should be determined.

Positive_Control: HEK293 cells. Human or mouse placenta, skeletal muscle or testis.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for WIPI2

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Alternative Name: WIPI2

Background: ATG18B, Atg21, CGI 50, DKFZp434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984, WD repeat domain phosphoinositide-interacting protein 2, WIPI2, WIPI49 like protein 2,WIPI2
Cellular localisation: Preautophagosomal structure membrane.

Molecular Weight: 49kDa

Gene ID: 26100, 122363

UniProt: Q9Y4P8