TNFRSF13C antibody
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- Target See all TNFRSF13C Antibodies
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF13C antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Immunogen
- Recombinant full-length human CD268 protein
- Clone
- BAFFR-1557
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF13C Primary Antibody
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- Application Notes
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Positive Control: Raji cells. Tonsil and lymph node.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
- Alternative Name
- TNFRSF13C (TNFRSF13C Products)
- Background
- Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494], also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins, the numbers of circulating B cells is usually in the normal range, but can be low.
- Molecular Weight
- 19kDa (Monomer), 40kDa (Dimer)
- Gene ID
- 115650
- UniProt
- Q96RJ3
- Pathways
- NF-kappaB Signaling
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