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TNFRSF13C antibody

TNFRSF13C Reactivity: Human IHC, StM Host: Mouse Monoclonal BAFFR-1557 unconjugated
Catalog No. ABIN6939146
  • Target See all TNFRSF13C Antibodies
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    Reactivity
    • 88
    • 26
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 66
    • 29
    • 5
    • 1
    Mouse
    Clonality
    • 65
    • 36
    Monoclonal
    Conjugate
    • 42
    • 11
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF13C antibody is un-conjugated
    Application
    • 49
    • 37
    • 34
    • 13
    • 13
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Immunogen
    Recombinant full-length human CD268 protein
    Clone
    BAFFR-1557
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TNFRSF13C Primary Antibody
  • Application Notes

    Positive Control: Raji cells. Tonsil and lymph node.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
    Alternative Name
    TNFRSF13C (TNFRSF13C Products)
    Background
    Defects in TNFRSF13C are the cause of immunodeficiency common variable type 4 (CVID4) [MIM:613494], also called antibody deficiency due to BAFFR defect. CVID4 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins, the numbers of circulating B cells is usually in the normal range, but can be low.
    Molecular Weight
    19kDa (Monomer), 40kDa (Dimer)
    Gene ID
    115650
    UniProt
    Q96RJ3
    Pathways
    NF-kappaB Signaling
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