CSTA antibody (AA 1-98)

Catalog No. ABIN6939197

This Mouse Monoclonal antibody specifically detects CSTA in IHC and StM. It exhibits reactivity toward Human.

Quick Overview for CSTA antibody (AA 1-98) (ABIN6939197)

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTA antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: CSTA-2882

Product Details anti-CSTA Antibody

Binding Specificity: AA 1-98

Purification: Purified by Protein A/G

Immunogen: Recombinant fragment of human CSTA protein (around aa 1-98) (exact sequence is proprietary)

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Human tonsil or prostate tissue (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CSTA

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Alternative Name: CSTA

Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Molecular Weight: 11kDa

Gene ID: 1475

UniProt: P01040

Pathways: Response to Water Deprivation