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Dystrophin antibody (AA 114-263)

DMD Reactivity: Human IHC, ELISA, Coat, StM Host: Mouse Monoclonal DMD-3241 unconjugated
Catalog No. ABIN6939241
  • Target See all Dystrophin (DMD) Antibodies
    Dystrophin (DMD)
    Binding Specificity
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 114-263
    Reactivity
    • 57
    • 27
    • 26
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 41
    • 17
    Mouse
    Clonality
    • 31
    • 27
    Monoclonal
    Conjugate
    • 31
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    This Dystrophin antibody is un-conjugated
    Application
    • 22
    • 21
    • 13
    • 10
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    A recombinant fragment (around aa 114-263) of human DMD protein (exact sequence is proprietary)
    Clone
    DMD-3241
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product DMD Primary Antibody
  • Application Notes

    Positive Control: Human skeletal muscle and heart muscle tissues (IHC).

    Known Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    Dystrophin (DMD)
    Alternative Name
    DMD (DMD Products)
    Synonyms
    DMD antibody, Dmd antibody, MGC83347 antibody, DKFZp459C1629 antibody, dmd antibody, MGC79631 antibody, DKFZp468A1620 antibody, Dp71 antibody, cb664 antibody, zfDYS antibody, im:6911785 antibody, zgc:110165 antibody, BMD antibody, CMD3B antibody, DXS142 antibody, DXS164 antibody, DXS206 antibody, DXS230 antibody, DXS239 antibody, DXS268 antibody, DXS269 antibody, DXS270 antibody, DXS272 antibody, DXSmh7 antibody, DXSmh9 antibody, Dp427 antibody, dys antibody, mdx antibody, pke antibody, DNADMD1 antibody, RATDMD antibody, CG17750 antibody, CG31175 antibody, CG34157 antibody, CG7240 antibody, CG7243 antibody, CG7344 antibody, DLP antibody, DLP1 antibody, DLP186 antibody, DLP2 antibody, DLP3 antibody, DmDLP antibody, DmDYS antibody, Dmel\\CG34157 antibody, Dp117 antibody, Dp186 antibody, Dp205 antibody, GI3046716 antibody, IDLP antibody, det antibody, dmDLP antibody, dmDp186 antibody, dmDys antibody, dystrophin antibody, dystrophin, gene 1 L homeolog antibody, dystrophin, gene 1 antibody, dystrophin, muscular dystrophy antibody, Dystrophin antibody, DMD antibody, LOC708073 antibody, dmd.1.L antibody, LOC465557 antibody, dmd.1 antibody, dmd antibody, Dmd antibody, Dys antibody
    Background
    Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.
    Molecular Weight
    427kDa
    Gene ID
    1756
    UniProt
    P11532
    Pathways
    Skeletal Muscle Fiber Development
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