BCL2L1 antibody (AA 1-135)
Quick Overview for BCL2L1 antibody (AA 1-135) (ABIN6940516)
Target
See all BCL2L1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-135
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Specificity
- Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241-amino acid protein which suppresses cell death. And Bcl-XS (short), a 178-amino acid protein lacking a 63-amino acid domain which functions as a dominant inhibitor of Bcl-2.
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Purification
- Purified by Protein A/G
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Immunogen
- Recombinant human BCL2L1 protein fragment (around aa 1-135) (exact sequence is proprietary)
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Isotype
- IgG
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Application Notes
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Positive Control: Jurkat, K562, HL-60 or HeLa cells. Reed-Sternberg cells in Hodgkin's lymphoma.
Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA) Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-80 °C
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Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Expiry Date
- 24 months
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- BCL2L1 (BCL2-Like 1 (BCL2L1))
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Alternative Name
- BCL2L1
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Molecular Weight
- 27kDa
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Gene ID
- 598
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UniProt
- Q07817
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Pathways
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
Target
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