Recombinant SOX9 antibody (AA 393-508)

Catalog No. ABIN6940622

This anti-SOX9 antibody is a Rabbit Monoclonal antibody detecting SOX9 in IHC and StM. Suitable for Human.

Quick Overview for Recombinant SOX9 antibody (AA 393-508) (ABIN6940622)

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SOX9 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: SOX9-3141R

Product Details anti-SOX9 Antibody

Binding Specificity: AA 393-508

Purification: Purified by Protein A/G

Immunogen: Recombinant human SOX9 protein fragment (around aa 393-508) (exact sequence is proprietary)

Isotype: IgG

Application Details

Application Notes:

Positive Control: HepG2 cells. Pancreas.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Alternative Name: SOX9

Background: Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Molecular Weight: 65kDa

Gene ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development