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CD147 antibody

This anti-CD147 antibody is a Mouse Monoclonal antibody detecting CD147 in IHC and StM. Suitable for Human.
Catalog No. ABIN6940676

Quick Overview for CD147 antibody (ABIN6940676)

Target

See all CD147 (BSG) Antibodies
CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This CD147 antibody is un-conjugated

Application

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Immunohistochemistry (IHC), Staining Methods (StM)

Clone

BSG-963
  • Specificity

    This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

    Purification

    Purified by Protein A/G

    Immunogen

    Recombinant human BSG protein

    Isotype

    IgG1 kappa
  • Application Notes

    Positive Control: HSB2 cells. Renal Cell, Colon or Testicular carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-80 °C

    Storage Comment

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Expiry Date

    24 months
  • Target

    CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

    Alternative Name

    BSG

    Molecular Weight

    35kDa (non-reduced), 40kDa (reduced)

    Gene ID

    682

    UniProt

    P35613

    Pathways

    S100 Proteins
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