Transferrin Receptor antibody

Catalog No. ABIN6940698

The Mouse Monoclonal anti-Transferrin Receptor antibody has been validated for FACS, IF and IHC (fro). It is suitable to detect Transferrin Receptor in samples from Human.

Quick Overview for Transferrin Receptor antibody (ABIN6940698)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: TFRC-1396

Product Details anti-Transferrin Receptor Antibody

Specificity: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Purification: Purified by Protein A/G

Immunogen: Recombinant human TFRC protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: PC3 cells. Human placenta or breast carcinoma.

Known Application: Flow Cytometry (0.5-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (0.5-1.0 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: TFRC

Molecular Weight: 85-95kDa (monomer), 190kDa (dimer)

Gene ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis