TGF-beta antibody

Catalog No. ABIN6940723

The Mouse Monoclonal anti-TGF-beta antibody has been validated for ELISA, Func, D and ELISA (Capture). It is suitable to detect TGF-beta in samples from Human, Mouse, Rat, Cow, Dog, Hamster and Monkey.

Quick Overview for TGF-beta antibody (ABIN6940723)

Target: TGF-beta (TGFb)

Reactivity: Human, Mouse, Rat, Cow, Dog, Hamster, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGF-beta antibody is un-conjugated

Application: ELISA, Functional Studies (Func), Detection (D), ELISA (Capture)

Clone: TGFB-510

Product Details anti-TGF-beta Antibody

Specificity: This MAb recognizes TGF beta 1, 2 and 3. TGF's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.

Purification: Purified by Protein A/G

Immunogen: Full length recombinant human TGF-beta2 protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Ovarian carcinoma, lung tumor or skin. PC-3 cell line. Eahy926 cells.

Known Application: Functional Assay (Order Ab without BSA/Azide), ELISA (0.1-0.4 μg/mL - Detection, 2-8 μg/mL - Capture), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TGF-beta

Target: TGF-beta (TGFb)

Alternative Name: TFGB

Molecular Weight: 13kDa

Gene ID: 7040, 7042, 7043

UniProt: P01137, P10600, P61812

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus