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CD68 antibody

This Mouse Monoclonal antibody specifically detects CD68 in IHC and StM. It exhibits reactivity toward Human, Mouse, Rat, Monkey, Cat and Rabbit.
Catalog No. ABIN6941239

Quick Overview for CD68 antibody (ABIN6941239)

Target

See all CD68 Antibodies
CD68 (CD68 Molecule (CD68))

Reactivity

  • 146
  • 63
  • 37
  • 34
  • 25
  • 16
  • 8
  • 5
  • 2
  • 2
  • 1
Human, Mouse, Rat, Monkey, Cat, Rabbit

Host

  • 88
  • 84
  • 13
  • 1
Mouse

Clonality

  • 109
  • 72
  • 1
Monoclonal

Conjugate

  • 95
  • 15
  • 12
  • 10
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD68 antibody is un-conjugated

Application

  • 87
  • 83
  • 57
  • 50
  • 36
  • 34
  • 34
  • 22
  • 20
  • 10
  • 9
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

Clone

KP1
  • Specificity

    This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

    No Cross-Reactivity

    Chicken, Dog (Canine), Pig (Porcine)

    Purification

    Purified by Protein A/G

    Immunogen

    Subcellular fraction of human alveolar macrophages

    Isotype

    IgG1 kappa
  • Application Notes

    Positive Control: Tonsil, Lymph Node or Spleen.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-80 °C

    Storage Comment

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Expiry Date

    24 months
  • Target

    CD68 (CD68 Molecule (CD68))

    Alternative Name

    CD68

    Molecular Weight

    110kDa

    Gene ID

    968

    UniProt

    P34810
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