Recombinant CD81 antibody

Catalog No. ABIN6941281

This anti-CD81 antibody is a Rabbit Monoclonal antibody detecting CD81 in ELISA and Coat. Suitable for Human, Mouse and Rat.

Quick Overview for Recombinant CD81 antibody (ABIN6941281)

Target: CD81

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD81 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Clone: C81-2885R

Product Details anti-CD81 Antibody

Specificity: Recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Purification: Purified by Protein A/G

Immunogen: B-Cell line derived from a Burkitt lymphoma

Isotype: IgG

Application Details

Application Notes:

Positive Control: Ramos, Daudi, Raji, U266, HUT-78, HUT-102, Jurkat, HL-60, KG1a, A293, A431, MG63 and human lymphocytes. Tonsil or Liver.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD81

Target: CD81

Alternative Name: CD81 / TAPA-1

Molecular Weight: 26kDa

Gene ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C