EBV EA antibody

Catalog No. ABIN6941310

The Mouse Monoclonal anti-EBV EA antibody has been validated for IF. It is suitable to detect EBV EA in samples from Epstein-Barr Virus (EBV).

Quick Overview for EBV EA antibody (ABIN6941310)

Target: EBV EA (Epstein-Barr Virus Early Antigen (EBV EA))

Reactivity: Epstein-Barr Virus (EBV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This EBV EA antibody is un-conjugated

Application: Immunofluorescence (IF)

Clone: 1108-1

Product Details anti-EBV EA Antibody

Purification: Purified by Protein A/G

Immunogen: Affinity Purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt's lymphoma sera

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: EBV-infected cells. Tissues.

Known Application: Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for EBV EA

Target: EBV EA (Epstein-Barr Virus Early Antigen (EBV EA))

Alternative Name: EBV Early Antigens (Epstein Barr Virus)

Target Type: Viral Protein

Background: Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.

Molecular Weight: 50/55kDa doublet