ASMT antibody (AA 230-280) (AbBy Fluor® 680)

Catalog No. ABIN6942134

This anti-ASMT antibody is a Rabbit Polyclonal antibody detecting ASMT in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for ASMT antibody (AA 230-280) (AbBy Fluor® 680) (ABIN6942134)

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASMT antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ASMT Antibody (AbBy Fluor® 680)

Binding Specificity: AA 230-280

Cross-Reactivity: Rat, Sheep

Predicted Reactivity: Human,Mouse,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acetylserotonin O-methyltransferase (ASMT)

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ASMT

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Alternative Name: ASMT

Background:

Synonyms: Acetylserotonin O-methyltransferase, ASMT, ASMTY, HIOMT, HIOMTY, Hydroxyindole O-methyltransferase.

Background: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity

Gene ID: 438

UniProt: P46597