ASMT antibody

Catalog No. ABIN873275

Product Details anti-ASMT Antibody

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat, Sheep

Predicted Reactivity: Human,Mouse,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Acetylserotonin O-methyltransferase (ASMT)

Isotype: IgG

Application Details

Application Notes: IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ASMT antibody (ABIN873275)

Herman, Bochenek, Król, Krawczyńska, Antushevich, Pawlina, Herman, Romanowicz, Tomaszewska-Zaremba: "Central Interleukin-1�� Suppresses the Nocturnal Secretion of Melatonin." in: Mediators of inflammation, Vol. 2016, pp. 2589483, (2017) (PubMed).

Herman, Wojtulewicz, Bochenek, Krawczyńska, Antushevich, Pawlina, Zielińska-Górska, Herman, Romanowicz, Tomaszewska-Zaremba: "Endotoxin-induced inflammation disturbs melatonin secretion in ewe." in: Asian-Australasian journal of animal sciences, Vol. 30, Issue 12, pp. 1784-1795, (2017) (PubMed).

Herman, Bochenek, Skipor, Król, Krawczyńska, Antushevich, Pawlina, Marciniak, Tomaszewska-Zaremba: "Interleukin-1 β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study." in: BioMed research international, Vol. 2015, pp. 526464, (2016) (PubMed).

Target Details for ASMT

Target: ASMT (Acetylserotonin O-Methyltransferase (ASMT))

Alternative Name: Asmt (ASMT Products)

Synonyms: asmt antibody, ASMTY antibody, HIOMT antibody, HIOMTY antibody, Hiomt antibody, acetylserotonin O-methyltransferase 2 antibody, acetylserotonin O-methyltransferase antibody, asmt2 antibody, asmt antibody, CV_2261 antibody, Desku_0280 antibody, Asmt antibody, ASMT antibody

Background:

Synonyms: Acetylserotonin O-methyltransferase, ASMT, ASMTY, HIOMT, HIOMTY, Hydroxyindole O-methyltransferase.

Background: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity

Gene ID: 438

UniProt: P46597