Defensin beta 3 antibody (AA 23-67)

Catalog No. ABIN6942250

The Rabbit Polyclonal anti-Defensin beta 3 antibody has been validated for ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It is suitable to detect Defensin beta 3 in samples from Human. There is 1 publication available.

Quick Overview for Defensin beta 3 antibody (AA 23-67) (ABIN6942250)

Target: Defensin beta 3 (DEFB3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Defensin beta 3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-Defensin beta 3 Antibody

Binding Specificity: AA 23-67

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta Defensin 3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Defensin beta 3 antibody (ABIN6942250)

Sandu, Serban, Iordache, Cursaru, Costache, Dumitru, Cirstoiu: "Immunohistochemistry Study of Antimicrobial Peptides as a Future Diagnostic and Prognostic Tool for Periprosthetic Joint Infections." in: Cureus, Vol. 16, Issue 9, pp. e69629, (2024) (PubMed).

Target Details for Defensin beta 3

Target: Defensin beta 3 (DEFB3)

Alternative Name: beta Defensin 3

Background:

Synonyms: BD 3, BD-3, BD3, beta 103, Beta defensin 103A, Beta defensin 103A precursor, Beta defensin 3, Beta-defensin 103, Beta-defensin 3, D103A_HUMAN, DEF B3, DEFB 103, DEFB 103A, DEFB 3, DEFB-3, DEFB103, DEFB103A, DEFB103B, DEFB3, Defensin, Defensin beta 103A, Defensin beta 3, Defensin like protein, Defensin-like protein, HBD 3, hBD-3, HBD3, HBP 3, HBP3, mBD3.

Background: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.

Gene ID: 414325

UniProt: P81534

Pathways: Production of Molecular Mediator of Immune Response