CD55 antibody (AA 301-390)

Catalog No. ABIN6942443

This anti-CD55 antibody is a Rabbit Polyclonal antibody detecting CD55 in WB, ELISA, IHC (fro), ICC, IHC (p), IF (cc) and IF (p). Suitable for Mouse.

Quick Overview for CD55 antibody (AA 301-390) (ABIN6942443)

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CD55 Antibody

Binding Specificity: AA 301-390

Cross-Reactivity: Mouse

Predicted Reactivity: Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CD55

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55

Background:

Synonyms: CD 55, CD55, CD55 antigen, CD55 Cromer blood group system, CD55 Molecule, CD55 Molecule, decay accelerating factor for complement (Cromer blood group), Cd55a, Complement decay accelerating factor, Complement decay-accelerating factor, Complement decay-accelerating factor, GPI-anchored, CR, CROM, Cromer Blood Group antigen, Cromer blood group system, DAF, Daf-GPI, DAF_HUMAN, Daf1, Dcay accelerating factor for complement (CD55, Cromer blood group system), Decay accelarating factor 1, isoform CRA_a, Decay accelerating factor (GPI-form), Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF, TC.

Background: This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF), binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gene ID: 13136

UniProt: Q61475

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity