CLTCL1 antibody

Catalog No. ABIN6942586

The Rabbit Monoclonal anti-CLTCL1 antibody has been validated for WB and IHC (p). It is suitable to detect CLTCL1 in samples from Human, Mouse and Rat.

Quick Overview for CLTCL1 antibody (ABIN6942586)

Target: CLTCL1 (Clathrin, Heavy Polypeptide Like 1 (CLTCL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CLTCL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2H4

Product Details anti-CLTCL1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human Clathrin heavy chain aa 100-300

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CLTCL1

Target: CLTCL1 (Clathrin, Heavy Polypeptide Like 1 (CLTCL1))

Alternative Name: CLTC/CLTCL1

Background:

Synonyms: Clathrin heavy chain 1, Clathrin heavy chain 2, Clathrin heavy chain on chromosome 17, Clathrin heavy chain on chromosome 22, CLH-17, CLH-22, CLTC, CLTCL1, CLTCL2, CLH17, CLH22, CLTCL, CLTD, Clathrin heavy chain like 1, KIAA0034

Background: Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are engulfed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.

Gene ID: 1213, 8218

UniProt: Q00610, P53675