COPG1, COPG2 (AA 1-100) antibody (Biotin)

Catalog No. ABIN6942600

This Rabbit Polyclonal antibody specifically detects COPG1, COPG2 in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for COPG1, COPG2 (AA 1-100) antibody (Biotin) (ABIN6942600)

Target: COPG1, COPG2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COPG2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: COPG1, COPG2

Alternative Name: COPG1 + COPG2

Background:

Synonyms: 2 COP, Coat protein nonclathrin gamma 2 cop, Coatomer protein complex subunit gamma 2, Coatomer subunit gamma 2, Coatomer subunit gamma-2, COPG 2, Copg2, COPG2_HUMAN, DKFZp761N09121, FLJ11781, Gamma 2 coat protein, Gamma 2 COP, Gamma-2-coat protein, Gamma-2-COP, Coatomer subunit gamma-1, COPG1, Gamma-1-coat protein, Gamma-1-COP, COPG

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Gene ID: 22820, 26958

UniProt: Q9Y678, Q9UBF2