DEXI antibody (AA 51-95)

Catalog No. ABIN6942879

This Rabbit Polyclonal antibody specifically detects DEXI in ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Mouse.

Quick Overview for DEXI antibody (AA 51-95) (ABIN6942879)

Target: DEXI (Dexamethasone-Induced Transcript (DEXI))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEXI antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-DEXI Antibody

Binding Specificity: AA 51-95

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DEXI

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DEXI

Target: DEXI (Dexamethasone-Induced Transcript (DEXI))

Alternative Name: DEXI

Background:

Synonyms: Dexamethasone-induced protein, DEXI, DEXI_HUMAN, MYLE, Protein MYLE.

Background: DEXI is a 95 amino acid protein belonging to the DEXI family. Induced by dexamethasone, DEXI is expressed in brain, liver, pancreas, placenta and lung, with highest levels in heart. DEXI is also up-regulated in emphysematous lung compared to normal lung. The gene encoding DEXI maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, a gastrointestinal inflammatory condition.

Gene ID: 28955

UniProt: O95424