EDEM3 antibody (AA 401-500) (HRP)

Catalog No. ABIN6943190

Product Details anti-EDEM3 Antibody (HRP)

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Binding Specificity: AA 401-500

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM3 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDEM3

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EDEM3

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Alternative Name: EDEM3 (EDEM3 Products)

Background:

Synonyms: C1orf22, EDEM 3, edem3, EDEM3_HUMAN, ER degradation enhancer, mannosidase alpha like 3, ER degradation enhancing alpha mannosidase like 3, ER degradation enhancing alpha mannosidase like 3, ER degradation-enhancing alpha-mannosidase-like 3.

Background: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]

Gene ID: 80267

UniProt: Q9BZQ6

Pathways: SARS-CoV-2 Protein Interactome