EGFRviii antibody (AA 321-520)
Quick Overview for EGFRviii antibody (AA 321-520) (ABIN6943225)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 321-520
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Cross-Reactivity
- Human
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Predicted Reactivity
- Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human EGFRvIII
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Isotype
- IgG
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anti-EGFR vIII (EGFRv3) (AA 1-50) antibody
EGFRv3 Reactivity: Human WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
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WB 1:300-5000
ELISA 1:500-1000 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
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Alternative Name
- EGFRvIII
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Background
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Synonyms: GFRvIII, Epidermal growth factor receptor variant type _, epidermal growth factor receptor isoform a variant.
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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Gene ID
- 1956
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UniProt
- P00533
Target
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