Endonuclease G antibody

Catalog No. ABIN6943254

This Rabbit Monoclonal antibody specifically detects Endonuclease G in WB and IF (cc). It exhibits reactivity toward Human and Mouse.

Quick Overview for Endonuclease G antibody (ABIN6943254)

Target: Endonuclease G (ENDOG)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Endonuclease G antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 2C1

Product Details anti-Endonuclease G Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: Synthetic peptide of C-terminal human Endo G

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Endonuclease G

Target: Endonuclease G (ENDOG)

Alternative Name: ENDOG

Background:

Synonyms: Endonuclease G mitochondrial, Endo G, ENDOG.

Background: Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.

Gene ID: 2021

UniProt: Q14249

Pathways: Apoptosis