EPOR antibody (AA 301-450) (PE)
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
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Binding Specificity
- AA 301-450
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EPOR antibody is conjugated to PE
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EPOR
- Isotype
- IgG
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- Application Notes
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Alternative Name
- EPOR
- Background
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Synonyms: EPO-R, Erythropoietin receptor, EPOR
Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
- Gene ID
- 2057
- UniProt
- P19235
- Pathways
- JAK-STAT Signaling
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