FTH1 antibody

Catalog No. ABIN6943446

This Rabbit Monoclonal antibody specifically detects FTH1 in FACS, IHC (p), IF (cc) and IF (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for FTH1 antibody (ABIN6943446)

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 5B5

Product Details anti-FTH1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: C terminal Human Ferritin Heavy Chain

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin Heavy Chain

Background:

Synonyms: Ferritin heavy chain, Cell proliferation-inducing gene 15 protein, Ferritin heavy chain, N-terminally processed, Ferritin H subunit, FTH1, FTH, FTHL6, FHC, HFE5, PLIF, PIG15

Background: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.

Gene ID: 2495

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis