FPA antibody (AA 20-120) (HRP)

Catalog No. ABIN6943452

This Rabbit Polyclonal antibody specifically detects FPA in ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FPA antibody (AA 20-120) (HRP) (ABIN6943452)

Target: FPA (Fibrinopeptide A (FPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPA antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FPA Antibody (HRP)

Binding Specificity: AA 20-120

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fibrinopeptide A

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FPA

Target: FPA (Fibrinopeptide A (FPA))

Alternative Name: Fibrinopeptide A

Background:

Synonyms: FGA, Fib2, FIBA_HUMAN, Fibrinogen alpha chain, fibrinogen alpha chain isoform alpha preproprotein, Fibrinogen alpha/alpha E chain [Precursor], fibrinogen alpha chain isoform alpha-E preproprotein, fibrinogen alpha chain isoform alpha preproprotein.

Background: The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008]

Gene ID: 2243

UniProt: P02671