FKBP5 antibody

Catalog No. ABIN6943473

This Rabbit Monoclonal antibody specifically detects FKBP5 in WB, IHC (p) and FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for FKBP5 antibody (ABIN6943473)

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FKBP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 6G6

Product Details anti-FKBP5 Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic peptide corresponding to the C-terminus of human FKBP51

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Alternative Name: FKBP5

Background:

Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP5, 51 kDa FK506-binding protein, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin, Rotamase, PPIase FKBP5, 51 kDa FKBP, FKBP-51, FKBP-5, p54, FKBP5, AIG6, FKBP51

Background: Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.

Gene ID: 2289

UniProt: Q13451