FYB1 antibody

Catalog No. ABIN6943496

This anti-FYB1 antibody is a Rabbit Monoclonal antibody detecting FYB1 in WB, IHC, FACS and IHC (p). Suitable for Human.

Quick Overview for FYB1 antibody (ABIN6943496)

Target: FYB1 (FYN-Binding Protein 1 (FYB1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FYB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F10

Product Details anti-FYB1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within C-terminal human FYB.

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FYB1

Target: FYB1 (FYN-Binding Protein 1 (FYB1))

Alternative Name: FYB1

Background:

Synonyms: FYN-binding protein 1, Adhesion and degranulation promoting adaptor protein, ADAP, FYB-120/130, p120/p130, FYN-T-binding protein, SLAP-130, SLP-76-associated phosphoprotein, SLAP130, FYB

Background: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.

Gene ID: 2533

UniProt: O15117