FYB1 antibody

Catalog No. ABIN7468349

Product Details anti-FYB1 Antibody

Target: FYB1 (FYN-Binding Protein 1 (FYB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYB1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FYB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FYB1

Target: FYB1 (FYN-Binding Protein 1 (FYB1))

Alternative Name: FYN binding protein 1 (FYB1 Products)

Synonyms: ADAP antibody, PRO0823 antibody, SLAP-130 antibody, FYN binding protein 1 antibody, FYB1 antibody

Background:

Synonyms: FYN binding protein 1 , ADAP , FYB , PRO0823 , SLAP-130 , SLAP130 , THC3

Background: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.

Molecular Weight: 85 kDa

Gene ID: 2533

UniProt: O15117