Histone H2A antibody (hydroxyTyr39)

Catalog No. ABIN6943625

The Rabbit Monoclonal anti-Histone H2A antibody (Clone 2A3) (ABIN6943625) specifically detects Histone H2A in WB, IHC and IHC (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Histone H2A antibody (hydroxyTyr39) (ABIN6943625)

Target: Histone H2A

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2A3

Product Details anti-Histone H2A Antibody

Binding Specificity: hydroxyTyr39

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic peptide surrounding Y39 of Histone H2A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Histone H2A

Target: Histone H2A

Background:

Synonyms: Histone H2A.1, Histone H2A.2, Histone H2A type 1-B/E, Histone H2A type 1-C, Histone H2A type 1-J, Histone H2A/e, Histone H2A/l, H2A2, HIST1H2AB, HIST1H2AC, HIST1H2AJ, Histone H2A.2, Histone H2A/a, Histone H2A/m

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene ID: 3012, 8335

UniProt: P04908