TRAP1 antibody

Catalog No. ABIN6943754

This anti-TRAP1 antibody is a Rabbit Monoclonal antibody detecting TRAP1 in WB. Suitable for Human.

Quick Overview for TRAP1 antibody (ABIN6943754)

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TRAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 6C2

Product Details anti-TRAP1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: N terminal human Hsp75

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TRAP1

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Alternative Name: Hsp75

Background:

Synonyms: Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, HSP 75, TRAP-1, TRAP1

Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Gene ID: 10131

UniProt: Q12931