Mast Cell Tryptase antibody

Catalog No. ABIN6944029

The Rabbit Monoclonal anti-Mast Cell Tryptase antibody has been validated for IHC, IHC (p), WB and IF (cc). It is suitable to detect Mast Cell Tryptase in samples from Human, Rat and Mouse.

Quick Overview for Mast Cell Tryptase antibody (ABIN6944029)

Target: Mast Cell Tryptase

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Mast Cell Tryptase antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 3G3

Product Details anti-Mast Cell Tryptase Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human Mast Cell Tryptase between 1-300 amino acids

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Mast Cell Tryptase

Target: Mast Cell Tryptase

Background:

Synonyms: Tryptase alpha/beta-1, Tryptase I, Tryptase alpha-1, Tryptase-1, TPSAB1

Background: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

Gene ID: 7177

UniProt: Q15661