Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Neuropilin 1 antibody

This anti-Neuropilin 1 antibody is a Rabbit Monoclonal antibody detecting Neuropilin 1 in WB, IHC, FACS, IHC (p) and IF (cc). Suitable for Human, Rat and Mouse.
Catalog No. ABIN6944264

Quick Overview for Neuropilin 1 antibody (ABIN6944264)

Target

See all Neuropilin 1 (NRP1) Antibodies
Neuropilin 1 (NRP1)

Reactivity

  • 115
  • 65
  • 56
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Rat, Mouse

Host

  • 123
  • 31
  • 4
  • 3
  • 1
Rabbit

Clonality

  • 117
  • 45
Monoclonal

Conjugate

  • 85
  • 22
  • 16
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuropilin 1 antibody is un-conjugated

Application

  • 124
  • 68
  • 47
  • 40
  • 35
  • 27
  • 14
  • 14
  • 13
  • 9
  • 4
  • 4
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone

49H9
  • Cross-Reactivity

    Human, Mouse, Rat

    Purification

    Purified by Protein A.

    Immunogen

    Human Neuropilin 1 between 900 to C-terminus

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Expiry Date

    12 months
  • Target

    Neuropilin 1 (NRP1)

    Alternative Name

    Neuropilin-1

    Background

    Synonyms: Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD_antigen: CD304, NRP1, NRP, VEGF165R

    Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

    Gene ID

    8829

    UniProt

    O14786

    Pathways

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
You are here:
Chat with us!