P2RY6 antibody (Pyrimidinergic Receptor P2Y, G-Protein Coupled, 6)

Details for Product anti-P2RY6 Antibody No. ABIN6944380
Antigen
  • P2Y6
  • 2010204J23Rik
  • P2y6
  • P2RY3
  • P2Y3
  • P2Y6R
  • pyrimidinergic receptor P2Y6
  • pyrimidinergic receptor P2Y, G-protein coupled, 6
  • P2RY6
  • P2ry6
Reactivity
Human
71
22
21
3
3
3
3
1
1
1
1
Host
Rabbit
71
Clonality (Clone)
Monoclonal ()
Conjugate
This P2RY6 antibody is un-conjugated
5
3
3
3
3
3
3
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
37
23
13
12
5
2
1
1
Options
Immunogen Synthetic peptide corresponding to N-terminal human P2Y6.
Clone 8H2
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others P2RY6 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name P2Y6 (P2RY6 Antibody Abstract)
Background

P2Y6 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

Subcellular location: Cell membrane


Synonyms: P2Y purinoceptor 6, P2Y6, P2RY6
Gene ID 5031
UniProt Q15077
Pathways Smooth Muscle Cell Migration
Application Notes WB(1:500-2000), IHC-P(1:50-200)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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