PEX14 antibody (AA 151-250) (Biotin)

Catalog No. ABIN6944490

This Rabbit Polyclonal antibody specifically detects PEX14 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for PEX14 antibody (AA 151-250) (Biotin) (ABIN6944490)

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PEX14 Antibody (Biotin)

Binding Specificity: AA 151-250

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEX14

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: PEX14

Background:

Synonyms: dJ734G22.2, NAPP2, NF E2 associated polypeptide 2, Peroxin 14, Peroxin-14, Peroxisomal biogenesis factor 14, Peroxisomal membrane anchor protein PEX14, Peroxisomal membrane anchor protein Pex14p, Peroxisomal membrane protein PEX14, pex14, PEX14_HUMAN, Pex14p, PTS1 receptor docking protein, PTS1 receptor-docking protein.

Background: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]

Gene ID: 5195

UniProt: O75381

Pathways: Maintenance of Protein Location