PIK3 gamma (AA 560-610) antibody (PE)

Details for Product No. ABIN6944548
Antigen
Epitope
AA 560-610
15
15
2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
47
47
47
Host
Rabbit
47
Clonality
Polyclonal
Conjugate
PE
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
Application
Flow Cytometry (FACS)
39
9
9
2
Options
Immunogen KLH conjugated synthetic peptide derived from human PIK3 gamma
Isotype IgG
Purification Purified by Protein A.
Antigen
Background

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].

Subcellular location: Cytoplasm


Synonyms: PK3CG_HUMAN, PI 3 Kinase catalytic subunit gamma, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, PI3Kgamma,
Gene ID 5294
UniProt P48736
Application Notes FCM(1:20-100)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months
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