PLEKHG5 antibody (AA 951-1062) (AbBy Fluor® 750)

Catalog No. ABIN6944611

The Rabbit Polyclonal anti-PLEKHG5 antibody has been validated for IF (cc) and IF (p). It is suitable to detect PLEKHG5 in samples from Mouse and Rat.

Quick Overview for PLEKHG5 antibody (AA 951-1062) (AbBy Fluor® 750) (ABIN6944611)

Target: PLEKHG5 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHG5 antibody is conjugated to AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PLEKHG5 Antibody (AbBy Fluor® 750)

Binding Specificity: AA 951-1062

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLEKHG5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLEKHG5

Target: PLEKHG5 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 5 (PLEKHG5))

Alternative Name: PLEKHG5

Background:

Synonyms: PKHG5_HUMAN, Pleckstrin homology domain-containing family G member 5, PH domain-containing family G member 5, Guanine nucleotide exchange factor 720, GEF720.

Background: This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Gene ID: 57449

UniProt: O94827

Pathways: Neurotrophin Signaling Pathway