SPATA5L1 antibody (AA 221-320) (Biotin)

Catalog No. ABIN6945025

The Rabbit Polyclonal anti-SPATA5L1 antibody has been validated for WB, ELISA, IHC (fro) and IHC (p). It is suitable to detect SPATA5L1 in samples from Human.

Quick Overview for SPATA5L1 antibody (AA 221-320) (Biotin) (ABIN6945025)

Target: SPATA5L1 (Spermatogenesis Associated 5-Like 1 (SPATA5L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA5L1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SPATA5L1 Antibody (Biotin)

Binding Specificity: AA 221-320

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPATA5L1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SPATA5L1

Target: SPATA5L1 (Spermatogenesis Associated 5-Like 1 (SPATA5L1))

Alternative Name: SPATA5L1

Background:

Synonyms: FLJ12286, MGC5347, SPA5L_HUMAN, SPATA5L1, Spermatogenesis-associated protein 5-like protein 1.

Background: SPATA5L1 is a 753 amino acid protein belonging to the AAA ATPase family and AFG2 subfamily. Single nucleotide polymorphisms (SNPs) present in SPATA5L1 at the glycine amidinotransferase (GATM)-SPATA5L1 locus have been found to correlate with glomerular filtration rate (GFR), having significant implications for kidney disease research. SPATA5L1 localizes to cytoplasm and exists as three alternatively spliced isoforms. The gene encoding SPATA5L1 maps to human chromosome 15q21.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3 % of the human genome. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gene ID: 79029

UniProt: Q9BVQ7