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STING/TMEM173 antibody

TMEM173 Reactivity: Human WB, FACS Host: Rabbit Monoclonal 1B8 unconjugated
Catalog No. ABIN6945184
  • Target See all STING/TMEM173 (TMEM173) Antibodies
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Reactivity
    • 66
    • 25
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 80
    • 4
    Rabbit
    Clonality
    • 70
    • 14
    Monoclonal
    Conjugate
    • 40
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STING/TMEM173 antibody is un-conjugated
    Application
    • 48
    • 28
    • 19
    • 18
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    Recombinant protein within human TMEM173 aa 200 to the C-terminus
    Clone
    1B8
    Isotype
    IgG
    Top Product
    Discover our top product TMEM173 Primary Antibody
  • Application Notes
    WB 1:300-5000
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Alternative Name
    TMEM173 (TMEM173 Products)
    Background

    Synonyms: Stimulator of interferon genes protein, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Transmembrane protein 173, hSTING, ERIS, hMITA, TMEM173, ERIS, MITA, STING.

    Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

    Gene ID
    340061
    UniProt
    Q86WV6
    Pathways
    Activation of Innate immune Response
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