TUBB3 antibody (HRP)

Catalog No. ABIN6945231

This Mouse Monoclonal antibody specifically detects TUBB3 in WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TUBB3 antibody (HRP) (ABIN6945231)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6F12

Product Details anti-TUBB3 Antibody (HRP)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human TUBB3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3

Background:

Synonyms: Tubulin beta 3, beta III Tubulin, Tubb3, Tubulin beta-3, beta 4, MC1R, TUBB 3, TUBB 4, TUBB3, TUBB4, Tubulin beta 3 chain, Tubulin beta 4, Tubulin beta III, Tubulin beta-3 chain, Neuron-specific class III beta-tubulin, Syntaxin III, Neuron specific beta III Tubulin, Tubulin beta-4 chain, Tubulin beta-III, beta-4, CDCBM, CFEOM3A, M(beta)3, M(beta)6, Neuron-specific class III beta-tubulin, QccE-11995, QccE-15186, TBB3_HUMAN, Tubulin beta 4, Tubulin beta-4 chain.

Background: Neuronal Marker
Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells.

Gene ID: 10381

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase