Interferon gamma antibody

Catalog No. ABIN6963815

This Rat Monoclonal antibody specifically detects Interferon gamma in ELISA and ELISpot. It exhibits reactivity toward Mouse and has been mentioned in 5+ publications.

Quick Overview for Interferon gamma antibody (ABIN6963815)

Target: Interferon gamma (IFNG)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: ELISA, ELISpot

Clone: AN18

Product Details anti-Interferon gamma Antibody

Specificity: 78ative and recombinant mouse IFN-γ

Characteristics: This monoclonal antibody enables specific detection of mouse IFN-γ in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse IFN-gamma

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

ABIN6963815 and ABIN7448268 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963816, ABIN7448269 and ABIN6964014 .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-Interferon gamma antibody (ABIN6963815)

Suschak, Bagley, Shoemaker, Six, Kwilas, Dupuy, Schmaljohn: "The Genetic Adjuvants Interleukin-12 and Granulocyte-Macrophage Colony Stimulating Factor Enhance the Immunogenicity of an Ebola Virus Deoxyribonucleic Acid Vaccine in Mice." in: The Journal of infectious diseases, Vol. 218, Issue suppl_5, pp. S519-S527, (2019) (PubMed).

Veglia, Tyurin, Blasi, De Leo, Kossenkov, Donthireddy, To, Schug, Basu, Wang, Ricciotti, DiRusso, Murphy, Vonderheide, Lieberman, Mulligan, Nam, Hockstein, Masters, Guarino, Lin, Nefedova, Black et al.: "Fatty acid transport protein 2 reprograms neutrophils in cancer. ..." in: Nature, Vol. 569, Issue 7754, pp. 73-78, (2019) (PubMed).

Obermajer, Urban, Wieckowski, Muthuswamy, Ravindranathan, Bartlett, Kalinski: "Promoting the accumulation of tumor-specific T cells in tumor tissues by dendritic cell vaccines and chemokine-modulating agents." in: Nature protocols, Vol. 13, Issue 2, pp. 335-357, (2019) (PubMed).

Bourgeois-Daigneault, Roy, Aitken, El Sayes, Martin, Varette, Falls, St-Germain, Pelin, Lichty, Stojdl, Ungerechts, Diallo, Bell: "Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy." in: Science translational medicine, Vol. 10, Issue 422, (2019) (PubMed).

Noguera-Ortega, Blanco-Cabra, Rabanal, Sánchez-Chardi, Roldán, Guallar-Garrido, Torrents, Luquin, Julián: "Mycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment." in: Scientific reports, Vol. 6, pp. 27232, (2018) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFNG

Gene ID: 15978

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy