Interferon gamma antibody

Catalog No. ABIN6963837

The Mouse Monoclonal anti-Interferon gamma antibody has been validated for ELISA and ELISpot. It is suitable to detect Interferon gamma in samples from Human. There are 5+ publications available.

Quick Overview for Interferon gamma antibody (ABIN6963837)

Target: Interferon gamma (IFNG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: ELISA, ELISpot

Clone: 1-D1K

Product Details anti-Interferon gamma Antibody

Specificity: Native and recombinant IFN-γ

Characteristics: This monoclonal antibody enables specific detection of human IFN-γ in immunoassays such as ELISpot, FluoroSpot, ELISA, and immunocytochemistry. Serum/Plasma samples

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IFN-gamma

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

ABIN6963837, ABIN7448286 and ABIN6963839 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963838, ABIN7448287, ABIN6963840 and ABIN6963841 . The antibody is also suitable for immunocytochemistry.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-Interferon gamma antibody (ABIN6963837)

Zacharakis, Chinnasamy, Black, Xu, Lu, Zheng, Pasetto, Langhan, Shelton, Prickett, Gartner, Jia, Trebska-McGowan, Somerville, Robbins, Rosenberg, Goff, Feldman: "Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer." in: Nature medicine, Vol. 24, Issue 6, pp. 724-730, (2019) (PubMed).

Cirac, Stützle, Dieckmeyer, Adhikary, Moosmann, Körber, Bauer, Witter, Delecluse, Behrends, Mautner: "Epstein-Barr virus strain heterogeneity impairs human T-cell immunity." in: Cancer immunology, immunotherapy : CII, Vol. 67, Issue 4, pp. 663-674, (2019) (PubMed).

Ott, Hu, Keskin, Shukla, Sun, Bozym, Zhang, Luoma, Giobbie-Hurder, Peter, Chen, Olive, Carter, Li, Lieb, Eisenhaure, Gjini, Stevens, Lane, Javeri, Nellaiappan, Salazar, Daley, Seaman, Buchbinder et al.: "An immunogenic personal neoantigen vaccine for patients with melanoma. ..." in: Nature, Vol. 547, Issue 7662, pp. 217-221, (2017) (PubMed).

Sahin, Derhovanessian, Miller, Kloke, Simon, Löwer, Bukur, Tadmor, Luxemburger, Schrörs, Omokoko, Vormehr, Albrecht, Paruzynski, Kuhn, Buck, Heesch, Schreeb, Müller, Ortseifer, Vogler, Godehardt et al.: "Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer. ..." in: Nature, Vol. 547, Issue 7662, pp. 222-226, (2017) (PubMed).

Arakawa, Siewert, Stöhr, Besgen, Kim, Rühl, Nickel, Vollmer, Thomas, Krebs, Pinkert, Spannagl, Held, Kammerbauer, Besch, Dornmair, Prinz: "Melanocyte antigen triggers autoimmunity in human psoriasis." in: The Journal of experimental medicine, Vol. 212, Issue 13, pp. 2203-12, (2016) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFNG

Gene ID: 3458

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy