Interferon gamma antibody (Alkaline Phosphatase (AP))

Catalog No. ABIN6963840

The Mouse Monoclonal anti-Interferon gamma antibody has been validated for ELISpot. It is suitable to detect Interferon gamma in samples from Human and Non-Human Primate. There are 5+ publications available.

Quick Overview for Interferon gamma antibody (Alkaline Phosphatase (AP)) (ABIN6963840)

Target: Interferon gamma (IFNG)

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is conjugated to Alkaline Phosphatase (AP)

Application: ELISpot

Clone: 7-B6-1

Product Details anti-Interferon gamma Antibody (Alkaline Phosphatase (AP))

Specificity: Native and recombinant IFN-γ

Cross-Reactivity (Details): The monoclonal antibody cross-reacts with IFN-γ from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IFN-gamma

Isotype: IgG1

Application Details

Application Notes: For enumeration of IFN-γ producing cells using ELISpot. 7-B6-1 is recommended as detection mAb in combination with coating mAb 1-D1K for human IFN-γ .

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C

Storage Comment: Store product at 4-8°C.

Expiry Date: 18 months

References for anti-Interferon gamma antibody (Alkaline Phosphatase (AP)) (ABIN6963840)

Wentink, Verheul, Griffioen, Schafer, McPherson, Early, van der Vliet, de Gruijl: "A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys." in: Vaccine, Vol. 36, Issue 15, pp. 2025-2032, (2018) (PubMed).

Ellis, Balgeman, Rodgers, Updike, Tomko, Maiello, Scanga, OConnor: "Characterization of T Cells Specific for CFP-10 and ESAT-6 in Mycobacterium tuberculosis-Infected Mauritian Cynomolgus Macaques." in: Infection and immunity, Vol. 85, Issue 4, (2017) (PubMed).

Sahin, Derhovanessian, Miller, Kloke, Simon, Löwer, Bukur, Tadmor, Luxemburger, Schrörs, Omokoko, Vormehr, Albrecht, Paruzynski, Kuhn, Buck, Heesch, Schreeb, Müller, Ortseifer, Vogler, Godehardt et al.: "Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer. ..." in: Nature, Vol. 547, Issue 7662, pp. 222-226, (2017) (PubMed).

Gubin, Zhang, Schuster, Caron, Ward, Noguchi, Ivanova, Hundal, Arthur, Krebber, Mulder, Toebes, Vesely, Lam, Korman, Allison, Freeman, Sharpe, Pearce, Schumacher, Aebersold, Rammensee, Melief, Mardis et al.: "Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. ..." in: Nature, Vol. 515, Issue 7528, pp. 577-81, (2015) (PubMed).

Czerkinsky, Andersson, Ekre, Nilsson, Klareskog, Ouchterlony: "Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells." in: Journal of immunological methods, Vol. 110, Issue 1, pp. 29-36, (1988) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFNG

Gene ID: 3458

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy