Interferon gamma antibody (HRP)

Catalog No. ABIN6963841

This anti-Interferon gamma antibody is a Mouse Monoclonal antibody detecting Interferon gamma in ELISA and ELISpot. Suitable for Human and Non-Human Primate. This Primary Antibody has been cited in 5+ publications.

Quick Overview for Interferon gamma antibody (HRP) (ABIN6963841)

Target: Interferon gamma (IFNG)

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is conjugated to HRP

Application: ELISA, ELISpot

Clone: 7-B6-1

Product Details anti-Interferon gamma Antibody (HRP)

Specificity: Native and recombinant IFN-γ

Cross-Reactivity (Details): The monoclonal antibody cross-reacts with IFN-γ from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IFN-gamma

Isotype: IgG1

Application Details

Application Notes: For quantification of IFN-γ in solution e.g. cell culture supernatants using ELISA and for enumeration of IFN-γ producing cells using ELISpot. 7-B6-1 is recommended as detection mAb in combination with coating mAb 1-D1K for human IFN-γ .

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: supplied storage buffer with 0.002 % Kathon CG

Storage: 4 °C

Storage Comment: Store product at 4-8°C.

Expiry Date: 18 months

References for anti-Interferon gamma antibody (HRP) (ABIN6963841)

Sauermann, Radaelli, Stolte-Leeb, Raue, Bissa, Zanotto, Krawczak, Tenbusch, Überla, Keele, De Giuli Morghen, Sopper, Stahl-Hennig: "Vector Order Determines Protection against Pathogenic Simian Immunodeficiency Virus Infection in a Triple-Component Vaccine by Balancing CD4+ and CD8+ T-Cell Responses." in: Journal of virology, Vol. 91, Issue 23, (2019) (PubMed).

Cirac, Stützle, Dieckmeyer, Adhikary, Moosmann, Körber, Bauer, Witter, Delecluse, Behrends, Mautner: "Epstein-Barr virus strain heterogeneity impairs human T-cell immunity." in: Cancer immunology, immunotherapy : CII, Vol. 67, Issue 4, pp. 663-674, (2019) (PubMed).

Callendret, Vellinga, Wunderlich, Rodriguez, Steigerwald, Dirmeier, Cheminay, Volkmann, Brasel, Carrion, Giavedoni, Patterson, Mire, Geisbert, Hooper, Weijtens, Hartkoorn-Pasma, Custers, Grazia Pau et al.: "A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates. ..." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192312, (2018) (PubMed).

Gubin, Zhang, Schuster, Caron, Ward, Noguchi, Ivanova, Hundal, Arthur, Krebber, Mulder, Toebes, Vesely, Lam, Korman, Allison, Freeman, Sharpe, Pearce, Schumacher, Aebersold, Rammensee, Melief, Mardis et al.: "Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. ..." in: Nature, Vol. 515, Issue 7528, pp. 577-81, (2015) (PubMed).

Czerkinsky, Andersson, Ekre, Nilsson, Klareskog, Ouchterlony: "Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells." in: Journal of immunological methods, Vol. 110, Issue 1, pp. 29-36, (1988) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFNG

Gene ID: 3458

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy