Interferon gamma antibody

Catalog No. ABIN6963842

This Rat Monoclonal antibody specifically detects Interferon gamma in ELISA and ELISpot. It exhibits reactivity toward Non-Human Primate and has been mentioned in 4+ publications.

Quick Overview for Interferon gamma antibody (ABIN6963842)

Target: Interferon gamma (IFNG)

Reactivity: Non-Human Primate

Host: Rat

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: ELISA, ELISpot

Clone: MT126L

Product Details anti-Interferon gamma Antibody

Specificity: Native and recombinant IFN-γ

Cross-Reactivity (Details): The monoclonal antibody reacts with human IFN-γ and cross-react with IFN-γ from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IFN-gamma

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-Interferon gamma antibody (ABIN6963842)

Sauermann, Radaelli, Stolte-Leeb, Raue, Bissa, Zanotto, Krawczak, Tenbusch, Überla, Keele, De Giuli Morghen, Sopper, Stahl-Hennig: "Vector Order Determines Protection against Pathogenic Simian Immunodeficiency Virus Infection in a Triple-Component Vaccine by Balancing CD4+ and CD8+ T-Cell Responses." in: Journal of virology, Vol. 91, Issue 23, (2019) (PubMed).

Callendret, Vellinga, Wunderlich, Rodriguez, Steigerwald, Dirmeier, Cheminay, Volkmann, Brasel, Carrion, Giavedoni, Patterson, Mire, Geisbert, Hooper, Weijtens, Hartkoorn-Pasma, Custers, Grazia Pau et al.: "A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates. ..." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192312, (2018) (PubMed).

Ellis, Balgeman, Rodgers, Updike, Tomko, Maiello, Scanga, OConnor: "Characterization of T Cells Specific for CFP-10 and ESAT-6 in Mycobacterium tuberculosis-Infected Mauritian Cynomolgus Macaques." in: Infection and immunity, Vol. 85, Issue 4, (2017) (PubMed).

Riccio, Pratt-Riccio, Bianco-Júnior, Sanchez, Totino, Carvalho, Daniel-Ribeiro: "Molecular and immunological tools for the evaluation of the cellular immune response in the neotropical monkey Saimiri sciureus, a non-human primate model for malaria research." in: Malaria journal, Vol. 14, pp. 166, (2016) (PubMed).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFNG

Gene ID: 3458

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy