IFNA Pan antibody

Catalog No. ABIN6963845

This Mouse Monoclonal antibody specifically detects IFNA Pan in ELISA and ELISpot. It exhibits reactivity toward Human and Non-Human Primate. It has been mentioned in 5+ publications

Quick Overview for IFNA Pan antibody (ABIN6963845)

Target: IFNA Pan

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, ELISpot

Clone: MT1-3-5

Product Details

Specificity: Native and recombinant IFN-α

Cross-Reactivity (Details): The monoclonal antibodies cross-react with IFN-α from non-human primates.

Characteristics: These monoclonal antibodies enable specific detection of human IFN-α subtypes 1/13, 2, 4, 5, 6, 7, 8, 10, 14, 16 and 17 (pan-specific detection) in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IFN-alpha

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

ABIN6963843 and ABIN7448289/3/5 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963844 and ABIN7448290/4/6 .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References

Panda, Facchinetti, Voynova, Hanabuchi, Karnell, Hanna, Kolbeck, Sanjuan, Ettinger, Liu: "Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models." in: The Journal of clinical investigation, Vol. 128, Issue 5, pp. 1873-1887, (2019) (PubMed).

Crisci, Ellegård, Nyström, Rondahl, Serrander, Bergström, Sjöwall, Eriksson, Larsson: "Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells." in: Journal of virology, Vol. 90, Issue 10, pp. 4939-4950, (2017) (PubMed).

Dudhgaonkar, Ranade, Nagar, Subramani, Prasad, Karunanithi, Srivastava, Venkatesh, Selvam, Krishnamurthy, Mariappan, Saxena, Fan, Stetsko, Holloway, Li, Zhu, Yang, Ruepp, Nair, Santella, Duncia et al.: "Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity. ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 3, pp. 1308-1319, (2017) (PubMed).

Tsuda, Hoenen, Banadyga, Weisend, Ricklefs, Porcella, Ebihara: "An Improved Reverse Genetics System to Overcome Cell-Type-Dependent Ebola Virus Genome Plasticity." in: The Journal of infectious diseases, Vol. 212 Suppl 2, pp. S129-37, (2015) (PubMed).

Vallhov, Qin, Johansson, Ahlborg, Muhammed, Scheynius, Gabrielsson: "The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications." in: Nano letters, Vol. 6, Issue 8, pp. 1682-6, (2006) (PubMed).

Target Details

Target: IFNA Pan

Gene ID: 3439, 3440, 3441