IL-10 antibody

Catalog No. ABIN6963849

Product Details anti-IL-10 Antibody

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-10 antibody is un-conjugated

Application: ELISA, ELISpot

Specificity: Native and recombinant IL-10

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse IL-10

Clone: MT60

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-10 antibody (ABIN6963849)

King, Mazor, Çuburu, Pastan: "Low-Dose Methotrexate Prevents Primary and Secondary Humoral Immune Responses and Induces Immune Tolerance to a Recombinant Immunotoxin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2038-2045, (2019) (PubMed).

Ashrafi, Shapouri, Shirkhani, Mahdavi: "Anti-tumor effects of propranolol: Adjuvant activity on a transplanted murine breast cancer model." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 45-51, (2018) (PubMed).

Reynolds, Suleyman, Ortega-Prieto, Skelton, Bonnesoeur, Blohm, Carregaro, Silva, James, Maillère, Dorner, Boyton, Altmann: "T cell immunity to Zika virus targets immunodominant epitopes that show cross-reactivity with other Flaviviruses." in: Scientific reports, Vol. 8, Issue 1, pp. 672, (2018) (PubMed).

Shekar, Ramlal, Jeyabalaji, Sripathy: "Intranasal immunization of cocktail/fusion protein containing Tir along with ΔG active fragment of Zot as mucosal adjuvant confers enhanced immunogenicity and reduces E. coli O157:H7 shedding in mice." in: International immunopharmacology, Vol. 63, pp. 211-219, (2018) (PubMed).

Day, Tselios, Androutsou, Tapeinou, Frilligou, Stojanovska, Matsoukas, Apostolopoulos: "Mannosylated Linear and Cyclic Single Amino Acid Mutant Peptides Using a Small 10 Amino Acid Linker Constitute Promising Candidates Against Multiple Sclerosis." in: Frontiers in immunology, Vol. 6, pp. 136, (2015) (PubMed).

Target Details for IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Alternative Name: IL10 (IL10 Products)

Gene ID: 16153

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints