IL-31 antibody (Biotin)

Catalog No. ABIN6963914

This Mouse Monoclonal antibody specifically detects IL-31 in ELISA and ELISpot. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for IL-31 antibody (Biotin) (ABIN6963914)

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-31 antibody is conjugated to Biotin

Application: ELISA, ELISpot

Clone: MT158

Product Details anti-IL-31 Antibody (Biotin)

Specificity: Native and recombinant human IL-31

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-31

Isotype: IgG1

Application Details

Application Notes: For quantification of IL-31 in solution e.g. cell culture supernatants using ELISA and for enumeration of IL-31 producing cells using ELISpot. MT158 is recommended as detection mAb in combination with coating mAbs MT31/88.

Comment:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-31 antibody (Biotin) (ABIN6963914)

Salz, Haeberle, Hoffmann, Enk, Hadaschik: "Elevated IL-31 serum levels in bullous pemphigoid patients correlate with eosinophil numbers and are associated with BP180-IgE." in: Journal of dermatological science, Vol. 87, Issue 3, pp. 309-311, (2019) (PubMed).

Welz-Kubiak, Kobuszewska, Reich: "IL-31 is overexpressed in lichen planus but its level does not correlate with pruritus severity." in: Journal of immunology research, Vol. 2015, pp. 854747, (2015) (PubMed).

Ko, Peng, Chen, Hsu, Pai, Yang, Wen, Jee, Wu, Chiu: "Interleukin-31 is associated with uremic pruritus in patients receiving hemodialysis." in: Journal of the American Academy of Dermatology, Vol. 71, Issue 6, pp. 1151-1159.e1, (2015) (PubMed).

Target Details for IL-31

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Alternative Name: IL31

Gene ID: 386653