APOA1 antibody

Catalog No. ABIN6963933

The Mouse Monoclonal anti-APOA1 antibody has been validated for WB and ELISA. It is suitable to detect APOA1 in samples from Human and Non-Human Primate. There are 5+ publications available.

Quick Overview for APOA1 antibody (ABIN6963933)

Target: APOA1 (Apolipoprotein A-I (APOA1))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: HDL 110

Product Details anti-APOA1 Antibody

Specificity: Native apolipoprotein A1 (apoA1), purified or in the form of HDL.

Cross-Reactivity (Details): The monoclonal antibody cross-reacts with apoA1 from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Human HDL

Isotype: IgG1

Application Details

Application Notes: For quantification of apoA1 in serum/ plasma samples and cell culture supernatants using ELISA. HDL 110 is recommended as coating mAb in combination with detection mAb HDL 44 . The antibody is also suitable for immunoprecipitation and Western blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-APOA1 antibody (ABIN6963933)

Slot, Kester, Van Harten, Jongbloed, Bouwman, Teunissen, Scheltens, van der Flier, Veerhuis: "ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aβ42, levels in non-demented elderly." in: Neurobiology of aging, Vol. 79, pp. 101-109, (2020) (PubMed).

Rebholz, Melchior, Welge, Remaley, Davidson, Woollett: "Effects of Multiple Freeze/Thaw Cycles on Measurements of Potential Novel Biomarkers Associated With Adverse Pregnancy Outcomes." in: Journal of clinical and laboratory medicine, Vol. 2, Issue 1, (2017) (PubMed).

Apro, Parini, Broijersén, Angelin, Rudling: "Levels of atherogenic lipoproteins are unexpectedly reduced in interstitial fluid from type 2 diabetes patients." in: Journal of lipid research, Vol. 56, Issue 8, pp. 1633-9, (2016) (PubMed).

Bissig-Choisat, Wang, Legras, Saha, Chen, Bell, Pankowicz, Hill, Barzi, Leyton, Leung, Kruse, Himes, Goss, Wilson, Chan, Lagor, Bissig: "Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model." in: Nature communications, Vol. 6, pp. 7339, (2015) (PubMed).

Halley, Kadakkuzha, Faghihi, Magistri, Zeier, Khorkova, Coito, Hsiao, Lawrence, Wahlestedt: "Regulation of the apolipoprotein gene cluster by a long noncoding RNA." in: Cell reports, Vol. 6, Issue 1, pp. 222-30, (2014) (PubMed).

Target Details for APOA1

Target: APOA1 (Apolipoprotein A-I (APOA1))

Alternative Name: apoA1

Gene ID: 335

Pathways: Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism